Home >  News >  Path of Exile 2: Slithering Dead Quest Guide Unveiled

Path of Exile 2: Slithering Dead Quest Guide Unveiled

by Claire Feb 12,2025

This guide details the "Slithering Dead" side quest in Path of Exile 2, focusing on its walkthrough and reward choices.

The Slithering Dead Quest: A Step-by-Step Guide

Image: Venom Crypts Entrance

To initiate this quest, locate the Venom Crypts entrance within the Jungle Ruins map (Act 3 and Act 3 Cruel). It's situated near the Waypoint. The Venom Crypts are optional; you can revisit them later if missed.

Explore the Venom Crypts until you find a corpse in the Den of the Serpent Priestess (location varies per map generation).

Image: Corpse-Snake Venom

Interact with the corpse to obtain Corpse-Snake Venom. Return to Servi in the Ziggurat Encampment and give her the venom to complete the quest.

Choosing Your Venom Draught Reward

Image: Venom Draught Choices

The Slithering Dead is repeatable (Act 3 and Act 3 Cruel), offering different rewards each time. Your choice is permanent.

Act 3 Rewards:

  • Venom Draught of Stone: 25% increased Stun Threshold.
  • Venom Draught of the Veil: 30% increased Elemental Ailment Threshold.
  • Venom Draught of Clarity: 25% increased Mana Regeneration Rate.

Generally, the Venom Draught of Clarity is the most versatile choice, especially beneficial for mana-intensive melee builds. The Venom Draught of the Veil is a strong alternative for builds less reliant on mana. The Venom Draught of Stone is the least desirable unless specifically needed to mitigate stun effects.

Act 3 Cruel (Act 6) Rewards:

  • Venom Draught of the Lost: +10% to Chaos Resistance.
  • Venom Draught of the Sky: +5 to All Attributes.
  • Venom Draught of the Marshes: 15% Reduced Slowing Potency of Debuffs.

The Venom Draught of the Lost (+10% Chaos Resistance) is usually the best option due to the rarity of Chaos Resistance on gear. The exception is builds utilizing Chaos Inoculation, where the Venom Draught of the Sky (+5 to all Attributes) might be preferable.